Although membrane proteins make up over 60% of drug targets, their structural complexity and instability create significant challenges for research. Conventional methods often result in misfolded or inactive proteins, delaying structural biology, functional studies, and drug development. Researchers use nanodiscs and detergents to stabilize membrane proteins. Nanodiscs create a native-like lipid bilayer, preserving function, while detergents solubilize proteins by mimicking lipid interactions. Though useful, these methods require many iterative cycles to find the right stabilizing condition making it costly, time-consuming, and vary in effectiveness. Nuclera's eProtein Discovery platform and customizable additive screening solution accelerates membrane protein production, delivering purified protein in just 48 hours. Fine-tune expression and purification conditions using nanodiscs, detergents, chaperones, metal ions, cofactors, redox conditions, and more to optimize membrane protein folding, stability, and function. From GPCRs to ion channels, streamline protein production by optimizing conditions to deliver high yield, purified, assay-ready membrane proteins efficiently.